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  • NYU Dataset

    An eIF3d-Dependent Switch Regulates Human Cytomegalovirus Replication

    Authors
    Letitia Thompson
    Daniel P. Depledge
    Hannah M. Burgess
    Ian Mohr
    Description

    Gene expression rapidly responds to physiological stress like virus infection in part via the control of mRNA translation. However, how translation of virus and host mRNAs are regulated during infection stress remains unknown. This study showed that protein synthesis in human cytomegalovirus (HCMV)-infected cells unexpectedly becomes progressively reliant upon eIF3d, which is a mRNA cap-binding protein...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Fluoride Exposure Alters Calcium Signaling and Mitochondrial Function in Enamel Cells

    Authors
    Francisco J. Aulestia
    Johnny Groeling
    Guilherme H. Souza Bomfim
    Veronica Costiniti
    8 more author(s)...
    Description

    Fluoride is a naturally occurring mineral that helps build strong teeth and prevent cavities. However, excessive fluoride intake causes dental fluorosis, which are enamel defects that can increase the risk of tooth decay. This study examined the effects of fluoride exposure in enamel cells to assess its impact on calcium signaling. For their investigation, they isolated primary EO cells from Sprague...

    Subject
    Genomics
    Access Rights
    Free to All